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doi: 10.1002/(SICI)1096-9896(200002)190:3 3.0.CO;2-8

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Subgroup analysis of those subjects having reduced corneal nerve fibers, and therefore more definitive evidence of small fiber neuropathy (37), show that ARA 290 treatment is associated with an increase in corneal nerve fiber density, analogous to the improvement seen after improved metabolic control (42) and after simultaneous pancreas and kidney transplantation (43)

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So let me give you a clear, honest, evidence-based look at what we actually know, what remains uncertain, and what I tell my patients when they ask about it